BDBM50303063 3-(6-(pyridin-3-ylmethylamino)pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine::CHEMBL583030

SMILES Nc1nn2cccnc2c1-c1cc(NCc2cccnc2)ncn1

InChI Key InChIKey=ZAJZFBGLQXRCPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303063   

TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303063(3-(6-(pyridin-3-ylmethylamino)pyrimidin-4-yl)pyraz...)
Affinity DataIC50: 36nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303063(3-(6-(pyridin-3-ylmethylamino)pyrimidin-4-yl)pyraz...)
Affinity DataIC50: 49nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed