BDBM50302971 (R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,4-oxadiazol-3-yl)pyrrolidin-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL567728

SMILES CC(C)(F)c1nc(no1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=RHMVNRUGRITMJY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302971   

TargetDipeptidyl peptidase 2(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302971((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302971((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human DPP9 expressed in baculovirus system after 30 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302971((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human POP expressed in Escherichia coli after 30 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302971((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human DPP8 expressed in baculovirus system after 15 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302971((R)-3-amino-1-((S)-2-(5-(2-fluoropropan-2-yl)-1,2,...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed