BDBM50302962 (R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)-3-amino-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL567279

SMILES CC(=O)N1CC(C1)c1noc(n1)[C@@H]1CCCN1C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=KNOTZXIQSRQETG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302962   

TargetDipeptidyl peptidase 2(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302962((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of DPP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302962((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human DPP9 expressed in baculovirus system after 30 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302962((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human POP expressed in Escherichia coli after 30 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302962((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human DPP8 expressed in baculovirus system after 15 mins by continuous fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Santhera Pharmaceuticals (Switzerland)

Curated by ChEMBL
LigandPNGBDBM50302962((R)-1-((S)-2-(3-(1-acetylazetidin-3-yl)-1,2,4-oxad...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant DPP4 transfected in Pichia methanolica expression system after 10 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed