BDBM50302798 2-(3-chloro-5-(2-(2,4-dichloro-5-methylphenylsulfonamido)-4-(ethylcarbamoyl)phenoxy)phenyl)acetic acid::CHEMBL570204

SMILES CCNC(=O)c1ccc(Oc2cc(Cl)cc(CC(O)=O)c2)c(NS(=O)(=O)c2cc(C)c(Cl)cc2Cl)c1

InChI Key InChIKey=YCVNCIQWEODZQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302798   

TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302798(2-(3-chloro-5-(2-(2,4-dichloro-5-methylphenylsulfo...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 expressed in HEK 293 cells in presence of 0.5% BSA by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302798(2-(3-chloro-5-(2-(2,4-dichloro-5-methylphenylsulfo...)
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of [3H]-PGD2 from human DP receptor expressed in HEK 293 cells in presence of 0.5% BSA by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302798(2-(3-chloro-5-(2-(2,4-dichloro-5-methylphenylsulfo...)
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at human CRTH2 expressed in CEM cells assessed as inhibition of PGD2-stimulated cell migration after 3 hrs by transwell migration...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed