BDBM50302619 CHEMBL567572::[2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-yl)-phenyl]-(4-ethoxy-phenyl)-methanone

SMILES CCOc1ccc(cc1)C(=O)c1cc(ccc1Cl)[C@@H]1O[C@@H](OC)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=JDGRCNIETMIZNO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302619   

TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302619([2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-m...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302619([2-Chloro-5-((2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-m...)
Affinity DataIC50: 57nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed