BDBM50302541 CHEMBL568603::N-(4-guanidinobutyl)-3-(4-hydroxyphenyl)acrylamide

SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]=[#6]-c1ccc(-[#8])cc1

InChI Key InChIKey=DUVLYVULPFIAOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302541   

TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302541(N-(4-guanidinobutyl)-3-(4-hydroxyphenyl)acrylamide...)
Affinity DataIC50: 5.76E+7nMAssay Description:Displacement of [3H]prazosin from rat salivary gland alpha1A adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50302541(N-(4-guanidinobutyl)-3-(4-hydroxyphenyl)acrylamide...)
Affinity DataIC50: 1.00E+8nMAssay Description:Antagonist activity at rat alpha1A adrenoceptor assessed as inhibition of phenylephrine-induced contraction of caudal arteryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed