BDBM50302507 4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylpiperazin-1-yl)ethoxy)styryl)nicotinonitrile::CHEMBL567124

SMILES CN1CCN(CCOc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)c2)CC1

InChI Key InChIKey=TUKOILYAIRACKC-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50302507   

TargetProtein kinase C eta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 330nMAssay Description:Inhibition of PKCeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 7nMAssay Description:Inhibition of PKCepsilon by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKCbeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PKCzeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 520nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 520nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human PKCtheta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302507(4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylp...)
Affinity DataIC50: 53nMAssay Description:Inhibition of PKCdelta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed