BDBM50302483 CHEMBL565629::N1-(2,4-dichlorobenzyl)-N4-(tetrahydro-2H-pyran-4-yl)piperidine-1,4-dicarboxamide

SMILES Clc1ccc(CNC(=O)N2CCC(CC2)C(=O)NC2CCOCC2)c(Cl)c1

InChI Key InChIKey=LEDLGRRUZLVBHP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302483   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302483(N1-(2,4-dichlorobenzyl)-N4-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302483(N1-(2,4-dichlorobenzyl)-N4-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50: 180nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed