BDBM50302461 CHEMBL567703::N-((4'-(methylsulfonyl)biphenyl-4-yl)methyl)-6-(3,3,3-trifluoropropoxy)nicotinamide

SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(CNC(=O)c2ccc(OCCC(F)(F)F)nc2)cc1

InChI Key InChIKey=JAJQVZPJXGJHGZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302461   

TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302461(N-((4'-(methylsulfonyl)biphenyl-4-yl)methyl)-6-(3,...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of rat sEHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302461(N-((4'-(methylsulfonyl)biphenyl-4-yl)methyl)-6-(3,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human soluble EHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302461(N-((4'-(methylsulfonyl)biphenyl-4-yl)methyl)-6-(3,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of soluble EH in human HepG2 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed