BDBM50302326 (R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N-(pyrrolidin-3-yl)methanesulfonamide::CHEMBL576821

SMILES Cc1c(CN([C@@H]2CCNC2)S(C)(=O)=O)ccc2cc(F)ccc12

InChI Key InChIKey=LNIDNIKEDAQTOW-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302326   

LigandPNGBDBM50302326((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...)
Affinity DataIC50: 735nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302326((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302326((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302326((R)-N-((6-fluoro-1-methylnaphthalen-2-yl)methyl)-N...)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed