BDBM50302324 (S)-3,4-dichloro-2-methyl-N-neopentyl-N-(pyrrolidin-3-yl)benzamide::CHEMBL566240

SMILES Cc1c(Cl)c(Cl)ccc1C(=O)N(CC(C)(C)C)[C@H]1CCNC1

InChI Key InChIKey=JVIKPFIJPCEZJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302324   

LigandPNGBDBM50302324((S)-3,4-dichloro-2-methyl-N-neopentyl-N-(pyrrolidi...)
Affinity DataIC50: 357nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302324((S)-3,4-dichloro-2-methyl-N-neopentyl-N-(pyrrolidi...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302324((S)-3,4-dichloro-2-methyl-N-neopentyl-N-(pyrrolidi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed