BDBM50302319 (R)-N-cyclopentyl-N-(pyrrolidin-3-yl)-2-naphthamide::CHEMBL567712

SMILES O=C(N(C1CCCC1)[C@@H]1CCNC1)c1ccc2ccccc2c1

InChI Key InChIKey=OSHSXYCWEWJREH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302319   

LigandPNGBDBM50302319((R)-N-cyclopentyl-N-(pyrrolidin-3-yl)-2-naphthamid...)
Affinity DataIC50: 677nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302319((R)-N-cyclopentyl-N-(pyrrolidin-3-yl)-2-naphthamid...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302319((R)-N-cyclopentyl-N-(pyrrolidin-3-yl)-2-naphthamid...)
Affinity DataIC50: 12nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed