BDBM50302310 CHEMBL567944::N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)acetamide

SMILES CC(=O)N(Cc1ccc2ccccc2c1)C1CCNCC1

InChI Key InChIKey=RQQIFQXOKVSJMS-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302310   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302310(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)acetam...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302310(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)acetam...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302310(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)acetam...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302310(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)acetam...)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed