BDBM50302308 CHEMBL567289::N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)pyrimidin-2-amine

SMILES C(N(C1CCNCC1)c1ncccn1)c1ccc2ccccc2c1

InChI Key InChIKey=GSCMKUDZZALNHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302308   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302308(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)pyrimi...)
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302308(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)pyrimi...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302308(N-(naphthalen-2-ylmethyl)-N-(piperidin-4-yl)pyrimi...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed