BDBM50302284 2,6-dimethoxy-4-(2-(2-morpholinopyrimidin-4-yl)thiazol-4-yl)phenol::CHEMBL568550

SMILES COc1cc(cc(OC)c1O)-c1csc(n1)-c1ccnc(n1)N1CCOCC1

InChI Key InChIKey=LIXPHSWBUVFNRA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302284   

TargetSerine/threonine-protein kinase mTOR(Human)
Kudos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302284(2,6-dimethoxy-4-(2-(2-morpholinopyrimidin-4-yl)thi...)
Affinity DataIC50: 180nMAssay Description:Inhibition of mTOR kinase in human HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302284(2,6-dimethoxy-4-(2-(2-morpholinopyrimidin-4-yl)thi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed