BDBM50302140 2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine::CHEMBL572228

SMILES Clc1ccccc1CCOc1cncc(n1)N1CCNCC1

InChI Key InChIKey=SJCOZNMAFPWOOQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302140   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  187nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302140(2-(2-chlorophenethoxy)-6-(piperazin-1-yl)pyrazine ...)
Affinity DataEC50:  308nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed