BDBM50302105 3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL569210

SMILES CCN(Cc1ccc(F)cc1)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O

InChI Key InChIKey=PEUJGVAASXDDNE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302105   

TargetC-X-C chemokine receptor type 2(Human)
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302105(3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-di...)
Affinity DataIC50: 6.34E+3nMAssay Description:Antagonist activity at CXCR2 expressed in CHO cells assessed as inhibition of IL-8-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302105(3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-di...)
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Wuxi Pharmatech

Curated by ChEMBL
LigandPNGBDBM50302105(3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-di...)
Affinity DataKi: >1.20E+4nMAssay Description:Displacement of [125I]IL-8 from human CXCR1 expressed in mouse BaF3 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed