BDBM50301985 2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluoro-4-morpholinopyridin-2-yloxy)-4-(dimethylamino)benzoic acid::CHEMBL572190

SMILES CN(C)c1ccc(C(O)=O)c(Oc2nc(Oc3cccc(c3)-c3cccc(CN)c3)c(F)c(N3CCOCC3)c2F)c1

InChI Key InChIKey=LLWGJNVDAOETRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301985   

TargetPlasminogen(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301985(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301985(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301985(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50: 900nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed