BDBM50301823 5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)-2-isopropylisoindolin-1-one::CHEMBL584478

SMILES CC(C)N1Cc2cc(ccc2C1=O)-c1nnn(c1C)-c1cccnc1F

InChI Key InChIKey=ZUWMBBZBDLJVHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301823   

TargetMetabotropic glutamate receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301823(5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301823(5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed