BDBM50301821 2-ethyl-5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl)isoindolin-1-one::CHEMBL577833

SMILES CCN1Cc2cc(ccc2C1=O)-c1nnn(c1C)-c1cccnc1F

InChI Key InChIKey=VDSWNDJVCZWANS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301821   

TargetMetabotropic glutamate receptor 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301821(2-ethyl-5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,...)
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human mGluR1 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301821(2-ethyl-5-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in CHO cell membranes assessed as inhibition of L-glutamate-induced calcium mobilization by FL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed