BDBM50301686 1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl)phenyl)furan-2-yl)methyl)-4-methylpiperazine::CHEMBL570865

SMILES CN1CCN(Cc2ccc(o2)-c2cccc(C#C)c2Cc2ccc3CC=Cc3c2C)CC1

InChI Key InChIKey=OLTHFAIHFDAJGG-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50301686   

TargetProtein kinase C eta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of PKCeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PKCtheta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human PKCdelta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PKCepsilon by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKCbeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PKCzeta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301686(1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed