BDBM50301680 4-(4-methyl-1H-indol-5-ylamino)-5-(4-(morpholinomethyl)phenyl)nicotinonitrile::CHEMBL586046

SMILES Cc1c(Nc2c(cncc2-c2ccc(CN3CCOCC3)cc2)C#N)ccc2[nH]ccc12

InChI Key InChIKey=PJGVITFBPVCDNT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301680   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301680(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(morpholinome...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PKCtheta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301680(4-(4-methyl-1H-indol-5-ylamino)-5-(4-(morpholinome...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human PKCdelta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed