BDBM50301678 4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)nicotinonitrile::CHEMBL567299

SMILES CN1CCN(Cc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1

InChI Key InChIKey=AZEVIHVCFXQWCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301678   

TargetProtein kinase C theta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301678(4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpip...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PKCtheta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301678(4-(4-methyl-1H-indol-5-ylamino)-5-(4-((4-methylpip...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human PKCdelta by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed