BDBM50301627 7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL585300

SMILES Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCN1CCN(CC1)c1ccccc1

InChI Key InChIKey=GQBKCNRAKIZTLJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50301627   

Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  76.4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cerebral cortex after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat striatum membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in rat cerebral cortex after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50301627(7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-...)
Affinity DataKi:  1.12E+4nMAssay Description:Displacement of [3H]Citalopram from SERT in rat cerebral cortex after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed