BDBM50301315 CHEMBL568467::N-(3,4-dimethyl-5-(morpholinomethyl)phenyl)-3,3-difluoro-2-methyl-2-(trifluoromethyl)butanamide

SMILES Cc1cc(NC(=O)C(C)(C(F)(F)F)C(F)(F)F)cc(CN2CCOCC2)c1C

InChI Key InChIKey=IPXCVXXZEZCJRH-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301315   

TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50301315(N-(3,4-dimethyl-5-(morpholinomethyl)phenyl)-3,3-di...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50301315(N-(3,4-dimethyl-5-(morpholinomethyl)phenyl)-3,3-di...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50301315(N-(3,4-dimethyl-5-(morpholinomethyl)phenyl)-3,3-di...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed