BDBM50301305 2-(4-cyclopropylbenzyl)-6,7,8,9-tetrahydro-2H-pyridazino[4,3-d]azepin-3(5H)-one::CHEMBL568692

SMILES O=c1cc2CCNCCc2nn1Cc1ccc(cc1)C1CC1

InChI Key InChIKey=VLISVMDMYXDRIM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301305   

Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301305(2-(4-cyclopropylbenzyl)-6,7,8,9-tetrahydro-2H-pyri...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301305(2-(4-cyclopropylbenzyl)-6,7,8,9-tetrahydro-2H-pyri...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed