BDBM50301285 1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepin-3(4H)-one::CHEMBL568693

SMILES O=c1[nH]n(Cc2ccccc2)c2CCNCCc12

InChI Key InChIKey=AQEVTTPQORHLEG-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50301285   

Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301285(1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301285(1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301285(1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50301285(1-benzyl-1,2,5,6,7,8-hexahydropyrazolo[4,3-d]azepi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed