BDBM50301256 CHEMBL570834::N-(4-(2-(2-hydroxy-2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethylamino)-2-methylpropyl)phenyl)-4-(2-(4-methylpiperazin-1-yl)acetamido)butanamide

SMILES CN1CCN(CC(=O)NCCCC(=O)Nc2ccc(CC(C)(C)NCC(O)c3ccc(O)c4NC(=O)COc34)cc2)CC1

InChI Key InChIKey=HTVRMSIYWXZESL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301256   

TargetBeta-2 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50301256(N-(4-(2-(2-hydroxy-2-(5-hydroxy-3-oxo-3,4-dihydro-...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in CHOK1 cell assessed as increase of intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50301256(N-(4-(2-(2-hydroxy-2-(5-hydroxy-3-oxo-3,4-dihydro-...)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at human beta-1 adrenoceptor expressed in CHOK1 cell assessed as increase of intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed