BDBM50301219 CHEMBL578988::cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarboxylic acid

SMILES c1c(cc(cc1Cl)Cl)NC(=O)[C@H]2CCCC[C@H]2C(=O)O

InChI Key InChIKey=VSMUYYFJVFSVCA-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301219   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301219(cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarb...)
Affinity DataEC50:  740nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50301219(cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarb...)
Affinity DataEC50:  750nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)