BDBM50301174 CHEMBL584928::methyl 4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-ylcarbamate

SMILES COC(=O)Nc1ccc2c(ccnc2c1)-c1c2CCCn2nc1-c1ccccn1

InChI Key InChIKey=HTVQKYMLRXMMGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301174   

TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50301174(methyl 4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed