BDBM50301119 (3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl azepane-1-carboxylate::CHEMBL572302

SMILES CN1C[C@H](C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO)OC(=O)N1CCCCCC1

InChI Key InChIKey=PFMDDCHUGSRIJN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301119   

LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 35nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 843nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301119((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed