BDBM50301112 (5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate::CHEMBL586042

SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1Cc2ccccc2C1)OC(=O)N1CCCC1

InChI Key InChIKey=QHTFXHUNNOAYME-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301112   

Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 186nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: 70nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed