BDBM50301104 (5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate::CHEMBL569388

SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1CCC(=CC1)c1ccccc1)OC(=O)N1CCCC1

InChI Key InChIKey=YDJAXPJDHWQNLF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301104   

LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 9nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 102nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 498nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50301104((5S,6S)-5-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-t...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed