BDBM50300893 (E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phenyl)-2-methanesulfinyl-3H-imidazol-4-yl]-pyridin-2-yl)-acrylamide::CHEMBL572006

SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1

InChI Key InChIKey=UEKDFQFEWKRBPE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300893   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300893((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...)
Affinity DataIC50: 41nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300893((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant CK1delta kinase domain by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300893((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...)
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300893((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...)
Affinity DataIC50: 447nMAssay Description:Inhibition of recombinant CK1epsilon by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed