BDBM50300891 (rac)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)pyridin-2-yl)-2-phenoxypropanamide::CHEMBL566058

SMILES CC(C)c1onc(c1-c1ccnc(NC(=O)C(C)Oc2ccccc2)c1)-c1ccc(F)cc1

InChI Key InChIKey=XIQQHIURKOKROB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300891   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300891((rac)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol...)
Affinity DataIC50: 890nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300891((rac)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol...)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant CK1delta kinase domain by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300891((rac)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol...)
Affinity DataIC50: 340nMAssay Description:Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed