BDBM50300758 3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide::CHEMBL574360

SMILES Cc1c(no[n+]1[O-])-c1ccccc1

InChI Key InChIKey=KCAHXIURYHAUTE-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50300758   

TargetThioredoxin reductase 1, cytoplasmic(Rat)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300758(3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of rat recombinant TrxR1 after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50300758(3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetThioredoxin glutathione reductase(Blood fluke)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300758(3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300758(3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant GR after 15 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Universita Degli Studi Di Torino

Curated by ChEMBL
LigandPNGBDBM50300758(3-methyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed