BDBM50300677 2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL573502

SMILES O=c1[nH]cnc2cn(nc12)-c1ccccc1

InChI Key InChIKey=OQHWVAQCLKFQMO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300677   

TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300677(2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...)
Affinity DataKi:  185nMAssay Description:Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50300677(2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one | C...)
Affinity DataKi:  725nMAssay Description:Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of Cl-IB-MECA-inhibited [3H]cAMP production b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed