BDBM50300667 2-(6-{[(4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-yl)sulfonyl]amino}-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide hydrochloride::CHEMBL573981

SMILES [#6]-[#7]-1-[#6]-[#6]-[#8]-c2ccc(cc-12)S(=O)(=O)[#7]-c1ccc2-[#6]-[#6]-[#6](=[#7]\[#7]=[#6](\[#7])-[#7])-c2c1

InChI Key InChIKey=VZCIHMCEDBFDPX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300667   

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300667(2-(6-{[(4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-...)
Affinity DataIC50: 581nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5-HT-stimulated cAMP production after 30 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300667(2-(6-{[(4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300667(2-(6-{[(4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed