BDBM50300666 2-{6-[(2-Naphthylsulfonyl)amino]-2,3-dihydro-1H-inden-1-ylidene}hydrazinecarboximidamide hydrochloride::CHEMBL574856

SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-1-[#6]-[#6]-c2ccc(-[#7]S(=O)(=O)c3ccc4ccccc4c3)cc-12

InChI Key InChIKey=GNFIQLUQLGGQRI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300666   

Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300666(2-{6-[(2-Naphthylsulfonyl)amino]-2,3-dihydro-1H-in...)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5-HT-stimulated cAMP production after 30 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300666(2-{6-[(2-Naphthylsulfonyl)amino]-2,3-dihydro-1H-in...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300666(2-{6-[(2-Naphthylsulfonyl)amino]-2,3-dihydro-1H-in...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed