BDBM50300573 2-(2-(2-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)ethyl)benzofuran-6-yl)acetic acid::CHEMBL584566

SMILES OC(=O)Cc1ccc2cc(CCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)oc2c1

InChI Key InChIKey=ZCCZMYDWILRCGU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300573   

TargetOxysterols receptor LXR-beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300573(2-(2-(2-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human LXRbeta assessed as association of SRC1 to LXRbeta ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300573(2-(2-(2-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-...)
Affinity DataEC50:  331nMAssay Description:Agonist activity at human LXRalpha assessed as association of SRC1 to LXRalpha ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed