BDBM50300545 CHEMBL573174::tetrahydroxycanadine hydrochloride

SMILES Oc1ccc2CC3N(CCc4cc(O)c(O)cc34)Cc2c1O

InChI Key InChIKey=TVKAUFJQMRSZFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300545   

TargetCell division control protein 42 homolog(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300545(tetrahydroxycanadine hydrochloride | CHEMBL573174)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Exonhit Therapeutics

Curated by ChEMBL
LigandPNGBDBM50300545(tetrahydroxycanadine hydrochloride | CHEMBL573174)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed