BDBM50300302 4-Amino-N'-hydroxy-N-(3-isopropylphenyl)-1,2,5-oxadiazole-3-carboximidamide::CHEMBL574139

SMILES CC(C)c1cccc(c1)N=C(NO)c1nonc1N

InChI Key InChIKey=MHDAOJWVQGRNDF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300302   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50300302(4-Amino-N'-hydroxy-N-(3-isopropylphenyl)-1,2,5-oxa...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of IDO1 by magnetic circular dichroism spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50300302(4-Amino-N'-hydroxy-N-(3-isopropylphenyl)-1,2,5-oxa...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of N-terminal his-tagged human indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as N'-formylkynurenine formation by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Macquarie University

Curated by ChEMBL
LigandPNGBDBM50300302(4-Amino-N'-hydroxy-N-(3-isopropylphenyl)-1,2,5-oxa...)
Affinity DataIC50: 225nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed