BDBM50300295 4-Amino-N-(2-chlorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide::CHEMBL576019

SMILES Nc1nonc1C(NO)=Nc1ccccc1Cl

InChI Key InChIKey=RPRAFTGCRGFZSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300295   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50300295(4-Amino-N-(2-chlorophenyl)-N'-hydroxy-1,2,5-oxadia...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of N-terminal his-tagged human indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as N'-formylkynurenine formation by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50300295(4-Amino-N-(2-chlorophenyl)-N'-hydroxy-1,2,5-oxadia...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of indoleamine 2,3-dioxygenase in IFN-gamma-stimulated human HeLa cells assessed as kynurenine formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed