BDBM50300221 2-(4-{[(3,5-Dimethylphenyl)amino]carbonothioyl}-1-piperazinyl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic Acid::CHEMBL569652

SMILES CCn1cc(C(O)=O)c(=O)c2cnc(nc12)N1CCN(CC1)C(=S)Nc1cc(C)cc(C)c1

InChI Key InChIKey=AFNXXFAUQZBFJV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300221   

TargetAutotaxin(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50300221(2-(4-{[(3,5-Dimethylphenyl)amino]carbonothioyl}-1-...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAutotaxin(Human)
The University of Memphis

Curated by ChEMBL
LigandPNGBDBM50300221(2-(4-{[(3,5-Dimethylphenyl)amino]carbonothioyl}-1-...)
Affinity DataKi:  4.20E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed