BDBM50300061 CHEMBL582893::Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]benzazepine-9-carboxylate

SMILES COC(=O)c1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1

InChI Key InChIKey=YKROMFXYBBYDLR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300061   

TargetMalate dehydrogenase, mitochondrial(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300061(Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]be...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50300061(Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]be...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300061(Methyl 6-oxo-5,6,7,12-tetrahydroindolo[3,2-d][1]be...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed