BDBM50300059 5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one::CHEMBL575106

SMILES CC(C)(C)c1ccc2[nH]c-3c(CC(=O)N(Cc4ccccc4)c4ccccc-34)c2c1

InChI Key InChIKey=NAGYTHZNOCSROX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300059   

TargetMalate dehydrogenase, mitochondrial(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300059(5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mitochondrial malate dehydrogenase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50300059(5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50300059(5-Benzyl-9-tert-butyl-7,12-dihydroindolo[3,2-d][1]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed