BDBM50300003 3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid::CHEMBL569193

SMILES OC(=O)c1cccc(c1)-c1ccc(s1)C(=O)C(F)(F)F

InChI Key InChIKey=DXFINMGOOFFGSP-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300003   

TargetHistone deacetylase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC6 in human HCT116 cells assessed as alpha-tubulin hyperacetylation after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of HDAC1 in human HCT116 cells assessed as inhibition of histone-H3 deacetylation after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Istituto Di Ricerche Di Biologia Molecolare

Curated by ChEMBL
LigandPNGBDBM50300003(3-[5-(Trifluoroacetyl)thiophen-2-yl]benzoic Acid |...)
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed