BDBM50299903 8-(2-(1-(biphenyl-4-yl)-2-methylpropan-2-ylamino)-1-hydroxyethyl)-5-hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL565686

SMILES CC(C)(Cc1ccc(cc1)-c1ccccc1)NCC(O)c1ccc(O)c2NC(=O)COc12

InChI Key InChIKey=DUCGRYYHGISZDT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299903   

TargetBeta-2 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50299903(8-(2-(1-(biphenyl-4-yl)-2-methylpropan-2-ylamino)-...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human adrenergic beta 2 expressed in CHO-K1 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50299903(8-(2-(1-(biphenyl-4-yl)-2-methylpropan-2-ylamino)-...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human adrenergic beta 1 expressed in CHO-K1 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed