BDBM50299889 5-hydroxy-8-(1-hydroxy-2-(3-methyl-1-o-tolylpropan-2-ylamino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL567833

SMILES Cc1cccc(CC(C)(C)NCC(O)c2ccc(O)c3NC(=O)COc23)c1

InChI Key InChIKey=QFAHPWBXTBJXGW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299889   

TargetBeta-2 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50299889(5-hydroxy-8-(1-hydroxy-2-(3-methyl-1-o-tolylpropan...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human adrenergic beta 2 expressed in CHO-K1 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50299889(5-hydroxy-8-(1-hydroxy-2-(3-methyl-1-o-tolylpropan...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human adrenergic beta 1 expressed in CHO-K1 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed