BDBM50299865 CHEMBL567406::N-(-1-(3-(5-Methyl-1H-imidazol-1-yl)propylamino)-2-nitrovinyl)-4-chloro-benzenamine::US8772508, 7

SMILES Cc1cncn1CCCN=C(C[N+]([O-])=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=OVKWACFPXWSZFC-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299865   

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Probiodrug

US Patent
LigandPNGBDBM50299865(US8772508, 7 | CHEMBL567406 | N-(-1-(3-(5-Methyl-1...)
Affinity DataKi:  51nM IC50: 320nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
Go to US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

Curated by ChEMBL
LigandPNGBDBM50299865(US8772508, 7 | CHEMBL567406 | N-(-1-(3-(5-Methyl-1...)
Affinity DataKi:  51nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed